
By Beatriz E. Amendola MD FACR

It’s hard to believe, but breast cancer remains the single most common
type of cancer in women. One of the most effective ways to treat the disease in
its early stages is radiation therapy, which has been used since 1929 in the treatment
of breast cancer.
Radiation therapy works by killing cancer cells within the breast, so that
the patient can keep her breast. Conventional radiation therapy or external beam
radiation (EBRT) is routinely used in early breast cancer after resection of the
tumor. EBRT is usually given Monday through Friday, over a course of five to seven
weeks, and radiation is usually applied to the entire breast and/or lymph glands.
The treatments are given with external beam radiation (EBRT) using linear accelerators
(high-energy radiation). EBRT is safe, painless and well tolerated, and is also
used in locally advanced breast cancer combined with chemotherapy, so that the
breast can be preserved. It can also be used after a mastectomy to prevent tumor
regrowth in the chest wall; for a pre-cancerous disease, such as Ductal Carcinoma
in situ and to treat advanced and metastatic disease.
Brachytherapy is a new twist on the old Radiation technique, which is garnering
lots of attention. The treatment is done on an outpatient basis in one week (usually
twice a day in the morning and late afternoon), and uses high dose remote control
radiation that is transmitted into plastic catheters surgically placed in the
breast. The term ‘brachy’ is Greek for short distance, and the benefit
is that the radiation can be contained and delivered with a great deal of precision,
limiting the radiation exposure to the health care professional. By using Brachytherapy,
the radiation only enters the area of treatment (the breast) through the catheters
for a few minutes each treatment, thus keeping unwanted radiation away from normal
healthy tissues such as the heart and/or the lungs.

For certain patients this technique is superior to other forms of Radiation.
Brachytherapy has been used in patients in many centers in the USAand Europe with
excellent results. Because the treatment time is so short, it is especially suited
for elderly patients, patients who live away from the center of radiation therapy
and/or patients who live in locations where radiation is not an available option
and they would need to travel to get the treatment.
One disadvantage
to the treatment is that it requires minor surgery to place the plastic catheters
into the breast tissue, and patients may not want yet another invasive procedure.
Brachytherapy is especially useful for patients with advanced breast tumors, who
need chemotherapy since the cancer drugs can be started after the surgical procedure,
while patients using conventional EBRT can not start the treatment until the radiation
is completed.
Before deciding to have Brachytherapy, keep in that not all patients are the
same, nor do all tumors behave in the same way. Make your decision by using all
resources available to you, including evaluation by a team of doctors, comprised
of a breast surgeon, diagnostic radiologist, pathologist, medical oncologist and
radiation oncologist.
Once everyone agrees, you can be comfortable that you’re quickly placing
radiation right where you want it – in your breast – rather than in
your entire body. Now that’s a high tech treatment worth talking about.
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Beatriz E. Amendola MD FACR
is a radiation oncologist based in Miami, FL, and the Director of the Brachytherapy
Institute of South Florida. She is also a Diplomate of the American Board of Radiology
and former Associate Professor and Director of Residency Training at the University
of Miami, Department of Radiation Oncology. |
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